|
|
|
| |
Monoclonal Antibody to CD303/BDCA-2 (Clone 110H7.05) Alexa 647 Conjugated |
|
|
| |
|
|
| |
|
| Catalog No: |
DDX0042A647-50 |
| Contents: |
Antibody in Tris-NaCl pH 8 |
| Isotype: |
IgG1 |
| Clone: |
110H7.05 |
| Purification: |
Purified using a QMA Hyper D ion exchange column |
| Species: |
Human |
| Host: |
Mouse |
| Supplier: |
Dendritics |
| Market Availability: |
North America (United States & Canada) |
| Application: |
Flow (Cell Surface): 5-25 ug/ml*
on request |
| Storage: |
Aliquot and store at -20°C. Contains no preservative; KEEP STERILE;AVOID REPEATED FREEZE/THAW CYCLES. |
|
 |
|
|
|
|
|
|
Background
CD303/DLEC/BDCA-2/CLECSF7/CLECSF11; Blood Dendritic Cell Antigen 2 protein / C-type (calcium dependent, carbohydraterecognition domain) lectin, superfamily member 7/11. BDCA2 is a type II membrane glycoprotein of 213 amino acids with a molecular mass of 25 kD which belongs to the group II of human calcium-dependent (C-type) lectin receptors (CLRs) with a single carbohydrate recognition domain (CRD) predicting mannosetype specificity. Protein expression is restricted to the immature plasmacytoid dendritic cell subset on which BDCA2 is involved in ligand internalization, processing and presentation, as well as in inhibition of IFN-a/b synthesis. |
Antigen
human recombinant BDCA-2 |
Application Notes
*Optimal dilution should be determined by each laboratory for each application |
Genebank Info (Protein)
NP_987099 |
| |
|
|
|
|
| - |
 |
|
Reference
1. (Treilleux I et al, 2004 Clinical Cancer Research, 10: 7466) ; Dzionek A. et al., 2000, J.Immunol.165, 6037-2001, J.Exp.Med. 194, 1823)
|
|
|
|
Research purposes only.
Not for diagnostic or in vivo use. This product is guaranteed to perform as indicated on the datasheet for six months from the date of purchase.
Alexa Fluor® is a registered trademark of Molecular Probes, Inc. IMGENEX sells Alexa Fluor® dye conjugated antibodies under license from Molecular Probes, Inc. for research use only.
|
|
|
|
|
