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Product : Antibody >> DNA Methylation & Rep.. , Neurobiology , Transcription Factors >> ATF2
      
 

Polyclonal Antibody to ATF2

 
Cat. No.DescriptionFormatUnitPrice(USD)QuantityBulk Quotation
IMG-311
ATF2Purified
0.1 mg
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Catalog No: IMG-311
Imgenex is now a part of Novus Biologicals! All orders, billing and shipments will be received from Novus. Please contact Novus directly for any questions novus@novusbio.com. To insure proper processing of you order, please insure that your purchase orders show Novus Biologicals as the vendor.
Contents: 0.1 mg antibody in 0.2 ml PBS containing 0.02% sodium azide. Sodium azide is highly toxic.
Isotype: Rabbit IgG
Purification: Protein G Chromatography
Species: Human
Host: Rabbit
Application: Western blot analysis: 2 ug/ml
Storage: Store ATF2 antibody at 4C. For long-term storage, store antibody at -20C.
Recommended
Positive Control:
293
 

Background
ATF2 is a member of the group of bZip transcription factors. Heterodimer formation between members of the bZip group is common and is believed to add diversity to the cis-acting elements at which binding of the dimers is directed. Specifically, ATF2 may dimerize with c-Jun, as occurs in response to E1a, and in so doing shift the binding preference of c-Jun toward ATF/CRE sites (1-3). Deletion analysis has indicated that the N-terminal region of ATF2 containing threonine at residues 69 and 71 are essential for this purpose. These threonine residues are phosphorylated by JNK/SAPK for transcriptional activation.

Antigen
This antibody was generated by immunizing rabbits with a synthetic peptide containing amino acids 13-27 of human ATF2.

Genebank Info (Protein): NP_001871
Gene ID: 1386
 
ATF2 Antibody

Detection of ATF2 in 293 cell lysate using ATF2 antibody at 2 ug/ml.

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Reference
1. Benbrook DM., and Jones NC. Oncogene 5, 295-302 (1990).
2. Hai T and Curran T. Proc. Natl. Acad. Sci. U. S. A. 88, 3720-3724 (1991).
3. van Dam, H., Duyndam, M., Rottier, R., Bosch, A., de Vries-Smits, L., Herrlich, P., Zantema, A., Angel, P., and van der Eb, A. J. (1993) EMBO J. 12, 479-487 (1993).


Research purposes only. Not for diagnostic or in vivo use. This product is guaranteed to perform as indicated on the datasheet for one year from the date of purchase.


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