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Peptide-affinity Purified Polyclonal Antibody to COX2/PTGS2 |
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| Catalog No: |
IMG-3130 |
| Contents: |
0.1 mg of purified antibody. 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. |
| Isotype: |
Goat Ig |
| Clone: |
N/A |
| Purification: |
Antigen Affinity Chromatography |
| Species: |
Human |
| Predicted React: |
Cow, Horse, Pig, Sheep |
| Host: |
Goat |
| Application: |
ELISA: >1:32000
Western blot analysis: 0.5-2ug/ml |
| Storage: |
Store at -20°C. |
Recommended
Positive Control: |
H460 |
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Background
Principal Names – PTGS2; prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase); COX2; COX-2; PHS-2; PGG/HS; PGHS-2; hCox-2; prostaglandin G/H synthase and cyclooxygenase
Official Gene Symbol - PTGS2
GenBank Accession Number – NP_000954
LocusLink ID - 5743 (human)
Gene Ontology Terms - cytoplasm; cell motility; inflammatory response; physiological processes; prostaglandin metabolism; prostaglandin-endoperoxide synthase |
Antigen
Peptide with sequence NPTVLLKERSTEL, from C Terminus of the protein sequence according to NP_000954. |
Application Notes
An ~70-75 kDa band is observed in H460 lysates (predicted MW of 69 kDa according to NP_000954). Bovine, horse, pig, and sheep reactivity expected from sequence similarity. |
Genebank Info (Protein)
NP_000954 |
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Staining of H460 lysate (RIPA buffer, 35 µg total protein per lane) with IMG-3130 (0.5 µg/ml). Detected by western blot using chemiluminescence. |
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Reference
1. Ballif BA, Mincek NV, Barratt JT, Wilson ML, Simmons DL. Interaction of cyclooxygenases with an apoptosis- and autoimmunity associated protein.Proc Natl Acad Sci U S A. 1996 May 28;93(11):5544-9. PMID: 8643612
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Research purposes only.
Not for diagnostic or in vivo use. This product is guaranteed to perform as indicated on the datasheet for one year from the date of purchase.
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