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Product : Antibody >> Antigen Affinity Purified , New Antibodies >> MAD4
      
 

Peptide-affinity Purified Polyclonal Antibody to MAD4/MXD4
 
Cat. No.DescriptionFormatUnitPrice(USD)QuantityBulk Quotation
IMG-3132
MAD4Purified, Peptide Affinity
0.1 mg
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Catalog No: IMG-3132
Contents: 0.1 mg of purified antibody. 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Isotype: Goat Ig
Clone: N/A 
Purification: Antigen Affinity Chromatography
Species: Human
Host: Goat
Application: ELISA: >1:16000
Western blot analysis: 0.5-2ug/ml
Storage: Store at -20°C.
Recommended
Positive Control:		 human kidney
 

Background
Principal Names – MAD4; MAX dimerization protein 4; MXD4; Mad4 homolog Official Gene Symbol - MXD4 GenBank Accession Number – NP_006445 LocusLink ID - 10608 (human) Gene Ontology Terms - protein binding; transcription co-repressor; cell growth and maintenance; negative control of cell proliferation; repression of transcription from Pol II promoter

Antigen
Peptide with sequence GPHCRRLGRPALS, from C Terminus of the protein sequence according to NP_006445.

Application Notes
An ~22 kDa band is observed in human kidney lysates (predicted MW of 24 kDa according to NP_006445).  Please note the appearance of this band was blocked by incubation with the immunising peptide.

Genebank Info (Protein)
NP_006445

 
MAD4 Antibody

Staining of human kidney lysate (RIPA buffer, 35 µg total protein per lane) using IMG-3132. Detected by western blot using chemiluminescence.

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Reference
1. Hurlin PJ, Queva C, Koskinen PJ, Steingrimsson E, Ayer DE, Copeland NG, Jenkins NA, Eisenman RN. Mad3 and Mad4: novel Max-interacting transcriptional repressors that suppress c-myc dependent transformation and are expressed during neural and epidermal differentiation. EMBO J. 1995 Nov 15;14(22):5646-59. PMID: 8521822
Research purposes only. Not for diagnostic or in vivo use. This product is guaranteed to perform as indicated on the datasheet for one year from the date of purchase.

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