Background
Principal Names- SLC6A4; solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 ; HGNC:11050; 5-HTT; HTT; OCD1; SERT; hSERT ; 5-hydroxytryptamine transporter; 5HT transporter; Na+/Cl- dependent serotonin transporter; serotonin transporter; sodium-dependent serotonin transporter; solute carrier family 6 member 4. Official Symbol- SLC6A4. GenBank Accession Number(s)- NP_001036.1. GeneID- 6532 (human).Gene Ontology Terms- Attention-deficit hyperactivity disorder (ADHD). Transporter of serotonin, Myocardial Infarction. |
Antigen
Peptide with sequence C-LHQGERETWGK, from the internal region of the protein sequence according to NP_001036.1. |
Application Notes
Peptide ELISA: antibody detection limit dilution 1:32000.
Western blot: Approx 70kDa band observed in Human Colon and Duodenum lysates (calculated MW of 70.3kDa according to NP_001036.1). Recommended concentration: 1-3µg/ml. |
Genebank Info (Protein)
NP_001036 |
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Western blot analysis of SLC6A4/5HTT/SERT staining in Human Colon lysate (35µg protein in RIPA buffer) using IMG-3859 at 2µg/ml. Primary incubation was 1 hour. Detected by chemiluminescence. |
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Reference
1. Voeller KK.
Attention-deficit hyperactivity disorder (ADHD).
J Child Neurol. 2004 Oct;19(10):798-814. Review.
PMID: 15559895
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