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Product : Antibody >> Apoptosis , Cancer Antibodies , Cell Cycle , G-Protein Coupled Recepto.. , New Antibodies >> CRTH2 (G Protein-Coupled Receptor GPR44)
      
 

Polyclonal Antibody to CRTH2
 
Cat. No.DescriptionFormatUnitPrice(USD)QuantityBulk Quotation
IMG-4069
CRTH2 (G Protein-Coupled Receptor GPR44)Purified
0.1 mg
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Catalog No: IMG-4069
Contents: 0.1 mg (1 mg/ml) antibody in PBS containing 0.02% sodium azide.
Isotype: Rabbit IgG
Clone: N/A
Purification: Protein G purified
Species: Mouse, Rat
Host: Rabbit
Application: Western blot analysis: use antibody at 1:500-1:1000
Storage: Maintain antibody at +2-8°C for 3 months or at -20°C for longer periods. Stable for 1 year. Avoid repeated freeze-thaw cycles.
 

Background
CRTH2 (chemoattractant receptor-homologous molecule), which is also known as the putative G protein-coupled receptor GPR44, is expressed on Th2 cells and is a novel member of the G protein-coupled leukocyte chemoattractant receptor family, which is selectively expressed in Th2 but not Th1 lineage cells. CRTH2 is selectively expressed in vivo in an activated state of Th2 cells including allergen-responsive Th2 cells, suggesting its pivotal roles in ongoing Th2-type immune reactions.

Antigen
Peptide corresponding to amino acids 329-348 [DDSELGGAGSSRRRRTSSTA] of the CRTH2 (GPR44) protein was used as immunogen for this antibody.

Application Notes
This sequence is near the C terminus. Cross reacts with rat and mouse.

Genebank Info (Protein)
NP_004769

 
CRTH2 (G Protein-Coupled Receptor GPR44) Antibody

Western blot analysis of CRTH2 in CRTH2 transfected Jurkat cells using CRTH2 antibody at 1:500 dilution. Does not detect CRTH2 in non-transfected parental Jurkat cells.

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Reference
1. Nagata K. et al. J Immunol 1999 Feb 1;162(3):1278-86
Research purposes only. Not for diagnostic or in vivo use. This product is guaranteed to perform as indicated on the datasheet for one year from the date of purchase.

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