|
| |
Polyclonal Antibody to CD100/SEMA-4D/Semaphorin 4D |
|
|
| |
|
|
| |
|
| Catalog No: |
IMG-4078 |
| Contents: |
0.1 mg (1 mg/ml) in PBS containing 0.02% sodium azide. |
| Isotype: |
Rabbit IgG |
| Clone: |
N/A |
| Purification: |
Protein G purified |
| Species: |
Human |
| Host: |
Rabbit |
| Application: |
Western blot analysis: 1:500-1:1000 |
| Storage: |
Maintain at +2-8°C for 3 months or at -20°C for longer periods. Stable for 1 year. Avoid repeated freeze-thaw cycles. |
|
 |
|
|
|
|
|
|
Background
Semaphorins are neuronal chemorepellants that direct pioneering neurons during nervous system development. CD100 is a novel semaphorin that induces B cells to aggregate and improves their viability in vitro. CD100 modifies CD40-CD40L B-cell signaling by augmenting B-cell aggregation and survival and down-regulating CD23 expression. CD72 is a lymphocyte receptor for the Class IV semaphorin CD100, which is involved in regulating B cell signaling. |
Antigen
Peptide corresponding to amino acids 147-158 GKNEDGKGRCPF of the human CD100 protein. |
Genebank Info (Protein)
NP_006369 |
| |
|
Western blot analysis of transfected CHO cells using IMG-4078 at 1:500 dilution. |
|
|
|
|
|
| - |
 |
|
Reference
1. Hall et al. (1996).Proc Natl Acad Sci U S A 93(21):11780-5
|
|
|
|
Research purposes only.
Not for diagnostic or in vivo use. This product is guaranteed to perform as indicated on the datasheet for one year from the date of purchase.
|
|
|
