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Product : Antibody >> Apoptosis , Cancer Antibodies , Cell Cycle , Chromatin , DNA Methylation & Rep.. >> HDAC-10
      
 

Polyclonal Antibody to HDAC-10

 
Cat. No.DescriptionFormatUnitPrice(USD)QuantityBulk Quotation
IMG-4145
HDAC-10Purified
0.1 mg
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Catalog No: IMG-4145
Imgenex is now a part of Novus Biologicals! All orders, billing and shipments will be received from Novus. Please contact Novus directly for any questions novus@novusbio.com. To insure proper processing of you order, please insure that your purchase orders show Novus Biologicals as the vendor.
Contents: 0.1 mg (1 mg/ml) in PBS containing 0.02% sodium azide.
Isotype: Rabbit IgG
Clone: N/A
Purification: Protein G purified
Species: Human
Host: Rabbit
Application: Western blot analysis: 1:250-1:1000
Storage: Maintain at +2-8C for 3 months or at -20C for longer periods. Stable for 1 year. Avoid repeated freeze-thaw cycles.
 

Background
A novel class II histone deacetylase, HDAC10 is most similar to HDAC6. Both contain a unique, putative second catalytic domain not found in other HDACs. In HDAC10, however, this domain is not functional. Unlike HDAC6, which is normally a cytoplasmic deacetylase, HDAC10 resides in both the nucleus and cytoplasm. Data suggests that HDAC10 may play roles both in the nucleus, as a transcriptional modulator, and in the cytoplasm in an unidentified role. HDAC10 variants seem present in certain cell lines and tissues that are as of yet not characterized..

Antigen
Recombinant human HDAC-10.

Genebank Info (Protein): NP_060191
Gene ID: 54862
SwissProt: Q6P1N0
 
HDAC-10 Antibody

Western blot analysis of HDAC-10 in HeLa cells using IMG-4145 at 1:250 dilution.

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Reference
1. Kao, H. et al. (2002) J. Biol. Chem. 277:187-193


Research purposes only. Not for diagnostic or in vivo use. This product is guaranteed to perform as indicated on the datasheet for one year from the date of purchase.


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