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Polyclonal Antibody to Caspase-10 |
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| Catalog No: |
IMG-4150 |
| Contents: |
0.1 mg (1 mg/ml) in PBS containing 0.02% sodium azide. |
| Isotype: |
Rabbit IgG |
| Clone: |
N/A |
| Purification: |
Protein G purified |
| Species: |
Chicken, Human, Mouse, Rat |
| Host: |
Rabbit |
| Application: |
Western blot analysis: 1:500-1:1000 |
| Storage: |
Maintain at +2-8°C for 3 months or at -20°C for longer periods. Stable for 1 year. Avoid repeated freeze-thaw cycles. |
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Background
Caspases are death effector domain-containing cysteine aspartases presumed to be at or near the apex of apoptotic signaling pathways. All known isoforms of Caspase-10 are abundantly expressed in fetal lung, kidney, and skeletal muscle but are very poorly expressed or absent in these tissues in the adult, implying a possible role for the Caspase-10 family in fetal development. |
Antigen
Peptide corresponding to the N terminal sequence [MKSQGQHWYSSSDKN] of all isoforms of human Caspase-10. |
Application Notes
Cross reactive with mouse, rat and chicken. |
Genebank Info (Protein)
NP_001093436 |
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Western blot analysis of Caspase-10 in Jurkat cells using IMG-4150 at 1:500. Cells were treated with 2 uM staurosporine for different time periods. |
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Reference
1. Ng P.W., Porter A.G., and Janicke R.U. J Biol Chem 1999 Apr 9;274(15):10301-8
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Research purposes only.
Not for diagnostic or in vivo use. This product is guaranteed to perform as indicated on the datasheet for one year from the date of purchase.
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