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Polyclonal Antibody to APRIL (TNFSF12) |
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| Catalog No: |
IMG-454 |
| Contents: |
100 ug antibody in 200 ul PBS containing 0.02% sodium azide. Sodium azide is highly toxic. |
| Isotype: |
Rabbit IgG |
| Purification: |
Protein G Chromatography was used to purify this antibody |
| Species: |
Human |
| Host: |
Rabbit |
| Storage: |
Store APRIL antibody at 4oC, stable for 6 months. For long-term storage, store antibody at -20oC. |
Recommended
Positive Control: |
HL-60 |
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Background
APRIL (a proliferation-inducing ligand) is a identified member of the tumor necrosis factor (TNF) family. Ectopic expression of APRIL is associated with the upregulation of X-linked inhibitor of apoptosis protein (XIAP) and may act as antiapoptotic factor. Although transcripts of APRIL are of low abundance in normal tissues, high levels of mRNA are detected in transformed cell lines, and in human cancers of colon, thyroid, and lymphoid tissues in vivo. |
Antigen
This antibody was generated by immunizing rabbits with a synthetic peptide (MPASSPFLLAPKGPPGN) corresponding to amino acids 1-17 of human APRIL, GenBank no NP_0037991. |
| Genebank Info (Protein): NP_003799.1 |
| Gene ID: 8741 |
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Western blot analysis of APRIL in HL-60 whole cell lysate using APRIL antibody at 2 ug/ml. |
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Reference
1. Xio Y, S Motomura, V Deyev, ER Podack. TNF superfamily member 13, APRIL, inhibits allergic lung inflammation. Eur J Immunol 41:164-171 (2011).
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Research purposes only.
Not for diagnostic or in vivo use. This product is guaranteed to perform as indicated on the datasheet for one year from the date of purchase.
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