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Polyclonal Antibody to STAT4 |
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| Catalog No: |
IMG-461 |
| Contents: |
Antibody in 200 ul PBS containing 0.2% gelatin and 0.05% sodium azide. Sodium azide is highly toxic. |
| Isotype: |
Rabbit IgG |
| Clone: |
N/A |
| Purification: |
Protein G Chromatography |
| Species: |
Mouse, Rat |
| Predicted React: |
Human |
| Host: |
Rabbit |
| Application: |
Western blot analysis: 1:500-1:1000 |
| Storage: |
Store at 4oC, stable for 6 months. For long-term storage, store at -20oC. |
Recommended
Positive Control: |
mouse or rat testes |
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Background
STATs (signal transducers and activators of transcription) are a family of cytoplasmic latent transcription factors that are activated to regulate gene expression in response to a large number of extracellular signaling polypeptides including cytokines, interferons, and growth factors. Stat 4 is activated when cells are treated with interleukin-12, a key cytokine regulator of cell-mediated immunity. |
Antigen
This antibody was generated by immunizing rabbits with synthetic peptide corresponding to amino acids 731-748 of mouse STAT4. This sequence is 100% homologous in human and rat. |
Genebank Info (Protein)
NP_003142 |
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Western blot analysis of STAT4 in rat testis lysate using IMG-461 at 1:1000 dilution. |
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Reference
1. Holly A., et al. J. Biol. Chem. 273:17109-17114 (1998)
2. David Farrar, et al. J. Biol. Chem. 275:2693-2697 (2000)
3. Nakahira M, et al. J Immunol.168(3):1146-1153(2002)
4. Kato A, et al. Transplantation 73(7):1142-1145(2002)
5. Battle TE, et al. Curr Mol Med 2(4):381-92(2002)
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Research purposes only.
Not for diagnostic or in vivo use. This product is guaranteed to perform as indicated on the datasheet for one year from the date of purchase.
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