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Product : Antibody >> DNA Methylation & Rep.. >> APEXL2
      
 

Polyclonal Antibody to APEXL2

 
Cat. No.DescriptionFormatUnitPrice(USD)QuantityBulk Quotation
IMG-466
APEXL2Purified
0.2 mL
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Catalog No: IMG-466
Imgenex is now a part of Novus Biologicals! All orders, billing and shipments will be received from Novus. Please contact Novus directly for any questions – novus@novusbio.com. To insure proper processing of you order, please insure that your purchase orders show Novus Biologicals as the vendor.
Contents: 100ug in 200 ul PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Isotype: Rabbit Ig
Clone: N/A
Purification: Protein G Chromatography
Species: Human
Predicted React: Mouse, Rat
Host: Rabbit
Application: Western blot analysis: 1:500-1:1000
Storage: It is supplied as Protein G purified IgG fraction. Store at 4oC, stable for 6 months. For long-term storage, store at -20oC.
Recommended
Positive Control:
HeLa
 

Background
Apurinic/apyrimidinic (AP) sites occur frequently in DNA by spontaneous hydrolysis, DNA damaging agents or DNA glycosylases that remove specific abnormal bases. ClassII AP endonucleases act to repair this damage by cleaving the phosphodiester backbone. It is primarily located in the nucleus but is also present in mitochondria. This protein may play an important role in both nuclear and mitochondrial base excision repair (BER).

Antigen
This antibody was generated by immunizing rabbits with EELRALDSEGRALLTQHKI (aa122-140) and GQAKTSEAKDEKELRTSF (aa438-455) peptides of human APEXL2. Genbank accession no. NM_014481

Application Notes
In HeLa, a 54 kDa band is observed.

Genebank Info (Protein): NP_055296
Gene ID: 27301

Genebank Info (Nucleotide): NM_014481

 
APEXL2 Antibody

Western blot analysis of APEXL2 in HeLa cell lysates using IMG-466 at a dilution of 1:500.

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Reference
1. Hadi, M..Z., et al., Homo sapiens APE2 protein (APE2) mRNA. Unpublished


Research purposes only. Not for diagnostic or in vivo use. This product is guaranteed to perform as indicated on the datasheet for one year from the date of purchase.


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