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Product : Antibody >> Cell Cycle , New Antibodies >> ARK1/2
      
 

Polyclonal Antibody to ARK1/2

 
Cat. No.DescriptionFormatUnitPrice(USD)QuantityBulk Quotation
IMG-5023
ARK1/2Purified
0.1 mg
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Catalog No: IMG-5023
Imgenex is now a part of Novus Biologicals! All orders, billing and shipments will be received from Novus. Please contact Novus directly for any questions novus@novusbio.com. To insure proper processing of you order, please insure that your purchase orders show Novus Biologicals as the vendor.
Contents: 100 ug in 200 ul PBS containing 0.2% gelatin and 0.05% sodium azide. Sodium azide is highly toxic.
Isotype: Rabbit IgG
Clone: N/A
Purification: Protein G Chromatography
Species: Human
Predicted React: Mouse, Rat
Host: Rabbit
Application: Western blot analysis: 2-4 ug/ml
Storage: It is supplied as Protein G purified fraction. Store at 4oC, stable for 6 months. For long-term storage, store at -20oC.
Recommended
Positive Control:
HCT-116
 

Background
The Aurora gene, a serine-threonine kinase, orginally discovered in Drosophila, has been found to be responsible for a chromosomal segregation defect. The mammalian homologues of Drosophila Aurora have been termed ARK1 (Aurora-related kinase 1) and ARK2.

Antigen
This antibody was developed against KLH-conjugated synthetic peptides corresponding to amino acids 2-16 and 157-170 of human ARK. These sequences are over 80% homologous in mouse and rat. These sequences are 100% homologous in ARK1 and ARK2.

Application Notes
In HCT-116, a 48 kDa band is observed.

Genebank Info (Protein): NP_940839
Gene ID: 6790
SwissProt: O14965
 
ARK1/2 Antibody

Western blot analysis of ARK in HCT-116 whole cell lysate using IMG-5023 at 4 ug/ml.

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Reference
1. Shindo,M., Nakano,H., Kuroyanagi,H., Shirasawa,T., Mihara,M., Gilbert,D.J., Jenkins,N.A., Copeland,N.G., Yagita,H. and Okumura,K. cDNA cloning, expression, subcellular localization, and chromosomal assignment of mammalian aurora homologues, aurora-related kinase (ARK) 1 and 2. Biochem. Biophys. Res. Commun. 244 (1), 285-292 (1998).


Research purposes only. Not for diagnostic or in vivo use. This product is guaranteed to perform as indicated on the datasheet for one year from the date of purchase.


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