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Product : Antibody >> Cell Cycle , New Antibodies >> ARK1/2
      
 

Polyclonal Antibody to ARK1/2
 
Cat. No.DescriptionFormatUnitPrice(USD)QuantityBulk Quotation
IMG-5023
ARK1/2Purified
0.1 mg
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Catalog No: IMG-5023
Contents: 100 ug in 200 ul PBS containing 0.2% gelatin and 0.05% sodium azide. Sodium azide is highly toxic.
Isotype: Rabbit IgG
Clone: N/A
Purification: Protein G Chromatography
Species: Human
Predicted React: Mouse, Rat
Host: Rabbit
Application: Western blot analysis: 2-4 ug/ml
Storage: It is supplied as Protein G purified fraction. Store at 4oC, stable for 6 months. For long-term storage, store at -20oC.
Recommended
Positive Control:		 HCT-116
 

Background
The Aurora gene, a serine-threonine kinase, orginally discovered in Drosophila, has been found to be responsible for a chromosomal segregation defect. The mammalian homologues of Drosophila Aurora have been termed ARK1 (Aurora-related kinase 1) and ARK2.

Antigen
This antibody was developed against KLH-conjugated synthetic peptides corresponding to amino acids 2-16 and 157-170 of human ARK. These sequences are over 80% homologous in mouse and rat. These sequences are 100% homologous in ARK1 and ARK2.

Application Notes
In HCT-116, a 48 kDa band is observed.

Genebank Info (Protein)
NP_940839

 
ARK1/2 Antibody

Western blot analysis of ARK in HCT-116 whole cell lysate using IMG-5023 at 4 ug/ml.

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Reference
1. Shindo,M., Nakano,H., Kuroyanagi,H., Shirasawa,T., Mihara,M., Gilbert,D.J., Jenkins,N.A., Copeland,N.G., Yagita,H. and Okumura,K. cDNA cloning, expression, subcellular localization, and chromosomal assignment of mammalian aurora homologues, aurora-related kinase (ARK) 1 and 2. Biochem. Biophys. Res. Commun. 244 (1), 285-292 (1998).
Research purposes only. Not for diagnostic or in vivo use. This product is guaranteed to perform as indicated on the datasheet for one year from the date of purchase.

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All products are For Research Use Only, unless indicated otherwise. Not for use in diagnostic or therapeutic procedures.

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