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Peptide-affinity Purified Polyclonal Antibody to AES (CT) |
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| Catalog No: |
IMG-5408-1 |
| Contents: |
0.05 mg of purified antibody in PBS containing 0.02% sodium azide. |
| Isotype: |
Rabbit Ig |
| Clone: |
N/A |
| Purification: |
Antigen Affinity Chromatography |
| Species: |
Human, Mouse, Rat |
| Host: |
Rabbit |
| Application: |
IF/ICC: 5-15 ug/ml
Western blot analysis: 1-2 ug/ml |
| Storage: |
Store at 4°C. |
Recommended
Positive Control: |
293 cell lysate can be used as positive control. |
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| Product Citations |
| 1. EWS/FL1 mediates transcriptional repression via NKX2.2 during oncogenic transformation in Ewing's sarcoma. Owen La, a Kowalewski, SL Lessnick. PLos ONE 4:e1965 (2009). WB: Fig 4A (retroviral-mediated expression of AES and empty vector control in A673 Ewing's sarcoma cells). Note: The specificity of the AES (IMG-5408) antibody was validated using retroviral-mediated AES expression compared to the empty vector control. | 2. AML1/ETO induces self-renewal in hematopoietic progenitor cells via the Groucho-related amino-terminal AES protein. Steffen B, M Knop, U Bergholz, O Vakhrusheva, M Rodel, G Kohler, M Henrichs, E Bulk, S Hehn, M Stehling, M Dugas, N Baumer, P Tschanter, C Brandts, S Koschmieder, W Berdel, H Server, C Stocking, C Tidow. J Blood 117:4328-4337 (2011). IMGENEX product cited: AES (IMG-5408). 1. IF/ICC: HeLa and suspension HL-60 cells, Fig 1E.
2. WB: U937 cells transfected with AML1/ETO vector, Fig 1B. |
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