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Product : Antibody >> CD Markers , Innate Immunology , Regulatory T Cells (Treg) , Th17 Antibodies >> CD4
      
 

Monoclonal Antibody to mouse CD4 (Clone GK1.5) FITC Conjugate

 
Cat. No.DescriptionFormatUnitPrice(USD)QuantityBulk Quotation
IMG-5922C
IMG-5922C-25UG
CD4FITC
0.1 mg
25 ug
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Catalog No: IMG-5922C
Imgenex is now a part of Novus Biologicals! All orders, billing and shipments will be received from Novus. Please contact Novus directly for any questions – novus@novusbio.com. To insure proper processing of you order, please insure that your purchase orders show Novus Biologicals as the vendor.
Contents: CD4 antibody at 0.5 mg/ml in 10 mM Tris, 150 mM NaCl, containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Isotype: Rat IgG2b, Kappa
Clone: GK1.5
Purification: Protein G Chromatography
Species: Mouse
Host: Rat
Application: Flow (Cell Surface): 0.1-1 ug/10^6 cells
Storage: Store at 4°C, stable for 6 months. DO NOT FREEZE; MATERIAL IS LIGHT-SENSITIVE.
 

Background
CD4 (cluster of differentiation 4) is a glycoprotein expressed on the surface of T helper cells, regulatory T cells, monocytes, macrophages, and dendritic cells. It is a member of the immunoglobulin superfamily. On T cells, it is the co-receptor for the T cell receptor (TCR) and amplifies the signal generated by the TCR by recruiting the tyrosine kinase lck that is essential for activating many molecules involved in the signaling cascade of an activated T cell. It is an important component of the immune system and is also the cellular receptor for HIV-1. It consists of a cytoplasmic tail, one transmembrane region, and four extracellular domains, D1-D4.  It maps to 12pter-p12 region of human chromosome.

Antigen
The mouse cytotoxic T lymphocyte line V4 was used as the immunogen for the CD4 antibody.

Genebank Info (Protein): NP_000607
Gene ID: 920
 
CD4 Antibody IMG-5922C

Cell surface flow analysis of CD4 in 10^6 BALB/c mouse splenocytes using 1 ug of IMG-5922C. Green represents isotype control (20212C); red represents mouse CD4 IMG-5922C antibody.

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Reference


Research purposes only. Not for diagnostic or in vivo use. This product is guaranteed to perform as indicated on the datasheet for six months from the date of purchase.


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