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Product : Antibody >> CD Markers , Innate Immunology , Regulatory T Cells (Treg) , Th17 Antibodies >> CD4
      
 

Monoclonal Antibody to mouse CD4 (Clone GK1.5) Azide Free

 
Cat. No.DescriptionFormatUnitPrice(USD)QuantityBulk Quotation
IMG-5922E-1000
CD4Azide-Free
1 mg
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Catalog No: IMG-5922E-1000
Imgenex is now a part of Novus Biologicals! All orders, billing and shipments will be received from Novus. Please contact Novus directly for any questions – novus@novusbio.com. To insure proper processing of you order, please insure that your purchase orders show Novus Biologicals as the vendor.
Contents: 1 mg antibody in 1 ml PBS. Filter sterilized. Sodium azide free.  Endotoxin level < 0.06 EU/ug.
Isotype: Rat IgG2b, Kappa
Clone: GK1.5
Purification: Protein G Chromatography
Species: Mouse
Host: Rat
Application:
IHC: reported in literature
Storage: Aliquot antibody and store frozen at -20°C.
 

Background
CD4 (cluster of differentiation 4) is a glycoprotein expressed on the surface of T helper cells, regulatory T cells, monocytes, macrophages, and dendritic cells. It is a member of the immunoglobulin superfamily. On T cells, CD4 is the co-receptor for the T cell receptor (TCR) and amplifies the signal generated by the TCR by recruiting the tyrosine kinase lck that is essential for activating many molecules involved in the signaling cascade of an activated T cell. CD4 is an important component of the immune system and is also the cellular receptor for HIV-1. It consists of a cytoplasmic tail, one transmembrane region, and four extracellular domains, D1-D4.  It maps to 12pter-p12 region of human chromosome.

Antigen
The mouse cytotoxic T lymphocyte line V4 was used as the immunogen for the CD4 antibody.

Genebank Info (Protein): NP_000607
Gene ID: 920
 
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Reference


Research purposes only. Not for diagnostic or in vivo use. This product is guaranteed to perform as indicated on the datasheet for one year from the date of purchase.


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