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Polyclonal Antibody to AROS |
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| Catalog No: |
IMG-6169A |
| Contents: |
100 ug in 200 ul PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic. |
| Isotype: |
Rabbit IgG |
| Purification: |
Protein A Chromatography
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| Species: |
Human |
| Host: |
Rabbit |
| Application: |
Western blot analysis: 2-4 ug/ml |
| Storage: |
Store at 4°C, stable for 6 months. For long-term storage, aliquot and store at -20°C. |
Recommended
Positive Control: |
Human liver |
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Background
AROS, a nucleolar protein with an unknown function, interacts with extraribosomal protein RPS19, playing a role in the signaling pathways that regulate rRNA transcription. The deduced amino acid sequence of AROS, derived from cDNA, defines an isoelectric point of 11.3. No known functional motifs were found in AROS except a short polylysine tract embedded in a putative nucleolar localization signal. At a basal level the protein is expressed ubiquitously with a significantly high level of expression in some tissues. Human AROS gene is mapped to chromosome 22q13.1. |
Antigen
A portion of amino acids 1-50 of human AROS was used as the immunogen. |
Application Notes
The amino acid sequence used as immunogen is 100% homologous in human. |
Genebank Info (Protein)
NP_919307 |
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Western blot analysis of AROS in human liver lysate using IMG-6169A at 3 ug/ml. |
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Reference
1. Maeda, N. et al. Biochem. Biophys. Res. Commun. 339:41-46 (2006).
2. Johan, F. et al. Blood. 109:3152-3154 (2007).
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Research purposes only.
Not for diagnostic or in vivo use. This product is guaranteed to perform as indicated on the datasheet for one year from the date of purchase.
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