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Polyclonal Antibody to PER1 |
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| Catalog No: |
IMG-6504A |
| Contents: |
100 ug in 200 ul PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic. |
| Isotype: |
Rabbit IgG |
| Purification: |
Protein A Chromatography |
| Species: |
Cow, Dog, Horse, Human, Mouse, Pig |
| Predicted React: |
Chimpanzee, Rat, Rhesus Monkey |
| Host: |
Rabbit |
| Application: |
IHC (paraffin): 5 ug/ml |
| Storage: |
Store at 4°C, stable for 6 months. For long-term storage, aliquot and store at -20°C. |
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Background
Period circadian protein homolog 1 (PER1) is a member of the PAS family of protein that is encoded by a Period family of genes, i.e. PER1, and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. PER1 is a component of the circadian rhythms of locomotor activity, metabolism and behavior. |
Antigen
A portion of amino acids 30-80 of mouse PER1 was used as the immunogen. |
Application Notes
The amino acid sequence used as immunogen is 100% homologous in mouse, horse, dog, pig and cattle, and 94% homologous in rhesus monkey, chimpanzee, rat and human. |
Genebank Info (Protein)
NP_035195 |
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Immunohistochemical analysis of PER1 in formalin-fixed, paraffin-embedded human brain tissue using an isotype control (top left) and IMG-6504A (bottom left, right) at 5 ug/ml. |
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Reference
1. Fujita, M. et al. Mol. Biol. Cell 17:5253-5264 (2006).
2. Chilov, D. et al. FACEB J. 15:2613-2622 (2001).
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Research purposes only.
Not for diagnostic or in vivo use. This product is guaranteed to perform as indicated on the datasheet for one year from the date of purchase.
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