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Product : Antibody >> CD Markers , Innate Immunology , NF-kB Pathway , TNF Family & Death Re.. >> CD27
      
 

Monoclonal Antibody to human CD27 (Clone 203.6)

 
Cat. No.DescriptionFormatUnitPrice(USD)QuantityBulk Quotation
IMG-6542A
CD27Purified
0.1 mg
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Catalog No: IMG-6542A
Imgenex is now a part of Novus Biologicals! All orders, billing and shipments will be received from Novus. Please contact Novus directly for any questions – novus@novusbio.com. To insure proper processing of you order, please insure that your purchase orders show Novus Biologicals as the vendor.
Contents: 0.1 mg in 0.1 ml of PBS with 0.05% sodium azide.  Sodium azide is highly toxic.
Isotype: Mouse IgG3
Clone: 203.6
Species: Human
Host: Mouse
Application:


Storage: Store at 4°C.
 

Background
CD27 is a type II homodimeric transmembrane glycoprotein (Mr = 55 kDa) and a member of the nerve growth factor/tumor necrosis receptor superfamily.1,2 The antigen was identified on medullar thymocytes, mature T lymphocytes (CD45RA+CD45RO- T-cell subpopulation), memory B cells, plasma, and NK cells. This antibody is well suited for immunohistochemical detection of CD27 in B cell non-Hodgkin’s lymphoma samples.

 
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Reference
1. Prasad, K.V.S., Ao, Z., Yoon, Y., et al. CD27, a member of the tumor necrosis factor receptor family, induces apoptosis and binds to Siva, a proapoptotic protein. Proc Natl Acad Sci USA 94 6346-6351 (1997).
2. Camerini, D., Walz, G., Loenen, W.A.M., et al. The T cell activation antigen CD27 is a member of the nerve growth factor/tumor necrosis factor receptor gene family. J Immunol 147 3165-3169 (1991).


Research purposes only. Not for diagnostic or in vivo use. This product is guaranteed to perform as indicated on the datasheet for one year from the date of purchase.


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