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Peptide-affinity Purified Polyclonal Antibody to hnRNPK |
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| Catalog No: |
IMG-6564A |
| Contents: |
100 ug in 200 ul PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic. |
| Isotype: |
Rabbit IgG |
| Purification: |
Antigen affinity chromatography |
| Species: |
Chimpanzee, Human, New World monkey, Mouse, Opossum, Rat |
| Predicted React: |
Chicken, Dog |
| Host: |
Rabbit |
| Application: |
IHC (paraffin): 5 ug/ml
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| Storage: |
Store at 4°C, stable for 6 months. For long-term storage, aliquot and store at -20°C. |
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Background
hnRNPK is most extensively studied among heterogeneous nuclear ribonucleoprotein families which plays an important role in cell signaling, telomere elongation, DNA repair and regulation of expression at both transcriptional and translational levels. It is a highly conserved RNA/DNA-binding protein which interacts with different classes of factors of extracellular signals. |
Antigen
A portion of amino acid 380 to 430 of human hnRNPK was used as immunogen. |
Application Notes
The amino acid sequence used as immunogen is 100% homologous in human, mouse, monkey, chimpanzee and rat, 94% homologous in dog and 78% homologous in chicken. |
| Genebank Info (Protein): P61978 |
| Gene ID: 3190 |
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Immunohistochemical analysis of hnRNPK in formalin-fixed, paraffin-embedded human stomach tissue using an isotype control (top left) and IMG-6564A (bottom left, right) at 5 ug/ml. |
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Reference
1. Mikula, M. et al. Proteomics. 6:2395-2406 (2006).
2. Bomsztyk, K. et al. Bioessays. 26:629-638 (2004).
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Research purposes only.
Not for diagnostic or in vivo use. This product is guaranteed to perform as indicated on the datasheet for one year from the date of purchase.
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