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Peptide-affinity Purified Polyclonal Antibody to Bombesin Receptor Subtype 3 (BRS3) |
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| Catalog No: |
IMG-71479 |
| Contents: |
0.05 mg of purified antibody at a concentration of 1 mg/ml. Phosphate buffered saline, pH 7.7, containing 0.01% sodium azide |
| Isotype: |
Rabbit IgG |
| Clone: |
N/A |
| Purification: |
Antigen Affinity Chromatography |
| Species: |
Human |
| Host: |
Rabbit |
| Application: |
IHC (paraffin): 7 ug/ml |
| Storage: |
Store at -20°C. For long term storage, store at -70°C |
Recommended
Positive Control: |
Human Placenta, Villi |
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Background
BRS3 is classified as an Orphan-A Receptor and is highly similar to the bombesin receptors but has a very low affinity for bombesin itself. Mice lacking BRS3 develop metabolic defects and obesity, suggesting that BRS3 may be an important target for obesity research. In addition, BRS3 may be involved in diabetes and hypertension. BRS3 expression has been reported in lung (normal and cancer), nasal mucosa, placenta, and uterus. ESTs have been isolated from normal brain and kidney cancer libraries. |
Antigen
Synthetic peptide corresponding to the C-terminal domain of human Bombesin Receptor Subtype 3 (BRS3) |
Genebank Info (Protein)
NP_001718 |
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IHC analysis of Placenta, Villi using IMG-71479 at 7 ug/ ml. |
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Reference
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Research purposes only.
Not for diagnostic or in vivo use. This product is guaranteed to perform as indicated on the datasheet for one year from the date of purchase.
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