Peptide-affinity Purified Polyclonal Antibody to Ah Receptor (AHR)

Background
Principal Names- ah receptor; ah receptors;  Aryl hydrocarbon receptor is a ligand-activated transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. AHR has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. AHR ligands included a variety of aromatic hydrocarbons.

Antigen
Synthetic peptide corresponding to the N-terminal region of human Ah Receptor.

Genebank Info (Protein)
NP_001612

Genebank Info (Nucleotide)
NM_001621

Reference
1. Biochem Biophys Res Commun 2001 Aug. 285:1121-9  The AH receptor of the most dioxin-sensitive species, guinea pig, is highly homologous to the human AH receptor.  Korkalainen M, Tuomisto J, and Pohjanvirta R
2. Biochem Biophys Res Commun 2000 Jun. 273:272-81  Restructured transactivation domain in hamster AH receptor.  Korkalainen M, Tuomisto J, and Pohjanvirta R
3. Comp Biochem Physiol C Pharmacol Toxicol Endocrinol 1998 Nov. 121:23-53  The aryl hydrocarbon receptor: a comparative perspective.  Hahn ME
4. Mol Pharmacol 1998 Jul. 54:86-93  Point mutation in intron sequence causes altered carboxyl-terminal structure in the aryl hydrocarbon receptor of the most 2,3,7,8-tetrachlorodibenzo-p-dioxin-resistant rat strain.  Pohjanvirta R, Wong JM, Li W, Harper PA, Tuomisto J, and Okey AB
5. Proc Natl Acad Sci U S A 1997 Dec. 94:13743-8  Molecular evolution of two vertebrate aryl hydrocarbon (dioxin) receptors (AHR1 and AHR2) and the PAS family.  Hahn ME, Karchner SI, Shapiro MA, and Perera SA