Background
ADRA1B, ALPHA1BAR, ADRA1, adra1b, adrenergic alpha 1b receptor, alpha 1b, alpha 1b adrenergic receptor, alpha 1b adrenoceptor, alpha-1b-adrenergic, alpha1b, alpha1b-adrenergic, alpha1B-AR, alpha1beta-AR; The alpha-1b adrenoceptor is an Adrenergic Receptor that causes contraction of smooth muscle cells and thereby controls vascular tone, blood pressure, and accelerates the development of atherosclerosis. Decreased alpha-1b adrenoceptor is associated with benign prostatic hyperplasia (BPH). This adrenergic receptor also acts as a proto-oncogene when transfected into cell lines where constitutive activation of the receptor induces neoplastic transformation. |
