Product : Antibody >> Chromatin , Phosphospecific Antibodie.. , Transcription Factors >> c-Jun (Thr239)

Peptide-affinity Purified Polyclonal Antibody to c-Jun (Thr239)

Cat. No.DescriptionFormatUnitPrice(USD)QuantityBulk Quotation
c-Jun (Thr239)Purified, Peptide Affinity
50 µg
Catalog No: IMG-90140-1
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Contents: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Isotype: Rabbit IgG
Clone: N/A
Purification: Prepared from rabbit serum by affinity purification via sequential chromatography on phospho and dephosphopeptide affinity columns.
Species: Human, Mouse, Rat
Host: Rabbit
Application: IHC (paraffin): 1:50-1:100
Western Blot: 1:500-1:1000
Storage: Store at -20C.
Positive Control:
HeLa cells

c-Jun is the putative transforming gene of avian sarcoma virus 17. The protein forms a complex with c-Fos, forming the transcription factor AP-1. AP-1 is a generic term for a dimeric transcription factor that contains members from the Jun, Fos, ATF, and MAF protein families. AP-1 complexes recognize the same sequence motif, termed TRE (TPA responsive element), which is also referred to as the AP-1 binding site. AP-1 activity can be regulated by dimer composition, transcription, post-translational modification and interactions with other proteins. AP-1 proteins play key roles in cell proliferation, differentiation, apoptosis, angiogenesis and tumour invasion. The c-Jun gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies.

This antibody was generated by immunizing rabbits with a synthetic phosphopeptide corresponding to human c-Jun around the phosphorylation site of threonine 239 (G-E-TP-P-P).

Genebank Info (Protein): NP_002219
Gene ID: 3725
SwissProt: P05412
c-Jun (Thr239) Antibody

Western blot analysis of c-Jun (Thr239) using IMG-90140-1 in HeLa cells untreated or treated with UV.

c-Jun (Thr239) Antibody IMG-90140-1

Immunohistochemical analysis of c-Jun (Thr239) in paraffin-embedded human breast carcinoma tissue using IMG-90140-1.


1. Eferl, R. et al. Nat. Rev. Cancer. 3:859-868 (2003).

Research purposes only. Not for diagnostic or in vivo use. This product is guaranteed to perform as indicated on the datasheet for one year from the date of purchase.






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