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Product : Antibody >> Apoptosis , Cancer Antibodies , Cell Cycle , Cytoskeleton & Nuclea.. , Kinases & Phosphatase.. >> CDK2 (Ab-160)
      
 

Peptide-affinity Purified Polyclonal Antibody to CDK2 (Ab-160)

 
Cat. No.DescriptionFormatUnitPrice(USD)QuantityBulk Quotation
IMG-90444-2
CDK2 (Ab-160)Purified, Peptide Affinity
100 µg
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Catalog No: IMG-90444-2
Imgenex is now a part of Novus Biologicals! All orders, billing and shipments will be received from Novus. Please contact Novus directly for any questions novus@novusbio.com. To insure proper processing of you order, please insure that your purchase orders show Novus Biologicals as the vendor.
Contents: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Isotype: Rabbit IgG
Clone: N/A
Purification: Prepared from rabbit serum by affinity purification via sequential chromatography on phospho and dephosphopeptide affinity columns.
Species: Human, Mouse, Rat
Host: Rabbit
Application: Western Blot: 1:500-1:1000
Storage: Store at -20C.
Recommended
Positive Control:
A2780 cells
 

Background
CDK2 a serine/threonine protein kinase, is a member of a highly conserved family of protein kinases that regulate the eukaryotic cell cycle. The protein kinase is homologous to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. For activity, it requires association with a cyclins which act as the positive regulatory subunit. It forms complex with cyclins A, E, D1, and D3. Cyclin E- CDK2 kinase is active in the G1 and S phases of the cell cycle and is important for the progression from G1 to S phase. The levels of Cyclin A- CDK2 are maximal at the G1/S transition and both CDK2 and Cyclin A associate with DNA in the initiation complex during replication.

Antigen
This antibody was generated by immunizing rabbits with a synthetic non-phosphopeptide corresponding to human CDK2 around the phosphorylation site of threonine160 (T-Y-TP-H-E).

Genebank Info (Protein): NP_001789
Gene ID: 1017
SwissProt: P24941
 
CDK2 (Ab-160) Antibody

Western blot analysis of CDK2 (Ab-160) using IMG-90444-2 in A2780 cells.

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Reference
1. Akiyama, T. et al. Cancer. Res. 57:1495-1501 (1997).
2. Bresnahan, WA. et al. J. General. Virol. 78:1993-1997 (1997).


Research purposes only. Not for diagnostic or in vivo use. This product is guaranteed to perform as indicated on the datasheet for one year from the date of purchase.


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