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Product : Antibody >> Stem Cell Markers >> Brain-specific angiogenesis inhibitor 1 (BAI1)
      
 

Polyclonal Antibody to Brain-specific angiogenesis inhibitor 1 (BAI1)

 
Cat. No.DescriptionFormatUnitPrice(USD)QuantityBulk Quotation
IMX-4973
Brain-specific angiogenesis inhibitor 1 (BAI1)Purified
0.1 mg
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Catalog No: IMX-4973
Imgenex is now a part of Novus Biologicals! All orders, billing and shipments will be received from Novus. Please contact Novus directly for any questions novus@novusbio.com. To insure proper processing of you order, please insure that your purchase orders show Novus Biologicals as the vendor.
Contents: 0.1 mg (1 mg/ml) in PBS containing 0.02% sodium azide.
Isotype: Rabbit IgG
Clone: N/A
Purification: Protein G purified
Host: Rabbit
Application: Peptide ELISA: 1:32,000
Storage: Maintain at +2-8C for 3 months or at -20C for longer periods. Stable for 1 year. Avoid repeated freeze-thaw cycles.
 

Background
Researchers have indicated that they want access to novel target antibodies quickly to aid in their research. IMGENEX is pleased to be able to offer researchers access to cutting-edge products that are still in the process of characterization/validation. IMGENEX’s ‘IMX’ antibody line is shown by ELISA to bind to the peptide used as immunogen. Investigators should empirically determine the suitability of the antibody, including optimal dilutions, for other applications of interest.

We cannot guarantee that the yet-to-be-fully validated antibody will work in any application other than in an ELISA against the peptide used as immunogen and therefore cannot offer a refund if the antibody does not work in your application.
The antibody is offered at a lower price compared to a more highly validated antibody.
We are not able to provide the immunogen for the antibodies, but do provide the amino acid sequence.


These antibodies are not fully validated and we appreciate your feedback. Customer feedback is used to help generate testing methodologies which can lead to further product validation or withdrawal.
Angiogenesis is controlled by a local balance between stimulators and inhibitors of new vessel growth and is suppressed under normal physiologic conditions. Angiogenesis has been shown to be essential for growth and metastasis of solid tumors. In order to obtain blood supply for their growth, tumor cells are potently angiogenic and attract new vessels as results of increased secretion of inducers and decreased production of endogenous negative regulators. Brain-specific angiogenesis inhibitor 1 (BAI1) is a seven-span transmembrane protein belonging to the secretin receptor family. There are two other brain-specific angiogenesis inhibitor genes, designated BAI2 and BAI3 which along with BAI1 have similar tissue specificities and structures, however only BAI1 is transcriptionally regulated by p53. BAI1 is postulated to be a member of the secretin receptor family, an inhibitor of angiogenesis and a growth suppressor of glioblastomas.

Antigen
Amino acids 1552 - 1567 [QPSPLELRSVEWERSG] of the human brain-specific angiogenesis inhibitor 1 (BAI1) protein.

Genebank Info (Protein): NP_001693
Gene ID: 575
SwissProt: O14514
 
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Reference


Research purposes only. Not for diagnostic or in vivo use. This product is guaranteed to perform as indicated on the datasheet for one year from the date of purchase.


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