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Product : Antibody >> Apoptosis , Cancer Antibodies , Cytokine & Chemokine , ELISA Antibodies , Signal Transduction >> STAT6
      
 

Polyclonal Antibody to STAT6

 
Cat. No.DescriptionFormatUnitPrice(USD)QuantityBulk Quotation
IMX-5057
STAT6Sera
0.1 mL
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Catalog No: IMX-5057
Imgenex is now a part of Novus Biologicals! All orders, billing and shipments will be received from Novus. Please contact Novus directly for any questions novus@novusbio.com. To insure proper processing of you order, please insure that your purchase orders show Novus Biologicals as the vendor.
Contents: 100 ul rabbit sera in glycerol and 0.05% sodium azide. Sodium azide is highly toxic.
Isotype: Rabbit Ig
Clone: N/A
Purification: Rabbit Serum
Species: Human, Mouse, Rat
Host: Rabbit
Application: Peptide ELISA: 1:100-1:1000
Storage: Store STAT6 antibody at 4oC, stable for 6 months. For long-term storage, store at -20oC.
 

Background
Researchers have indicated that they want access to novel target antibodies quickly to aid in their research. IMGENEX is pleased to be able to offer researchers access to cutting-edge products that are still in the process of characterization/validation. IMGENEX’s ‘IMX’ antibody line is shown by ELISA to bind to the peptide used as immunogen. Investigators should empirically determine the suitability of the antibody, including optimal dilutions, for other applications of interest.

We cannot guarantee that the yet-to-be-fully validated antibody will work in any application other than in an ELISA against the peptide used as immunogen and therefore cannot offer a refund if the antibody does not work in your application.
The antibody is offered at a lower price compared to a more highly validated antibody.
We are not able to provide the immunogen for the antibodies, but do provide the amino acid sequence.


These antibodies are not fully validated and we appreciate your feedback. Customer feedback is used to help generate testing methodologies which can lead to further product validation or withdrawal.
. Often times, multiple samples will be included, differing in the amino acid sequence used to raise the immune sera. STATs (signal transducers and activators of transcription) are a family of cytoplasmic latent transcription factors that are activated to regulate gene expression in response to a large number of extracellular signaling polypeptides including cytokines, interferons, and growth factors. STAT6 is rapidly activated in response to IL-4, however the fate of the activated form is not clear.

Antigen
This antibody was developed against a synthetic peptide corresponding to amino acids 808-826 of human STAT6. STAT6 antibody will cross-react with mouse and rat, based on NCBI BLAST.

Application Notes
Researchers are encouraged to optimize dilution for their specific testing. Human STAT6 is an 847 amino acid protein.

Genebank Info (Protein): NP_003144
Gene ID: 6778
 
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Reference
1. Bluyssen HA and Levy DE. J Biol Chem 272: 4600-4605 (1997).
2. Darnell JE Jr. Science 277:1630-1635 (1997).
3. Quelle FW, et al. Mol Cell Biol 15(6): 3336-43. (1995).
4. Ryan P., et al.  J. Biol. Chem. published July 16, 2002.
5. Leonard WJ, et al. Annu Rev Immunol 16:293-322 (1998).
6. Schindler C, et al. Annu Rev Biochem 64:621-51 (1995).


Research purposes only. Not for diagnostic or in vivo use. This product is guaranteed to perform as indicated on the datasheet for one year from the date of purchase.


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