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Product : Antibody >> Chromatin , New Antibodies >> Bnc 1
      
 

Polyclonal Antibody to Bnc 1

 
Cat. No.DescriptionFormatUnitPrice(USD)QuantityBulk Quotation
IMX-6048
Bnc 1Sera
0.1 mL
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Catalog No: IMX-6048
Imgenex is now a part of Novus Biologicals! All orders, billing and shipments will be received from Novus. Please contact Novus directly for any questions – novus@novusbio.com. To insure proper processing of you order, please insure that your purchase orders show Novus Biologicals as the vendor.
Contents: 100 ul of crude rabbit sera with 50% glycerol and 0.025% sodium azide. Sodium azide is highly toxic.
Isotype:
Species: Chimpanzee, Human, New World monkey
Predicted React: Horse, Dog, Cow
Host:
Application: Peptide ELISA: 1:100-1:1000
Storage: Store at -20°C.
 

Background
Researchers have indicated that they want access to novel target antibodies quickly to aid in their research. IMGENEX is pleased to be able to offer researchers access to cutting-edge products that are still in the process of characterization/validation. IMGENEX’s ‘IMX’ antibody line is shown by ELISA to bind to the peptide used as immunogen. Investigators should empirically determine the suitability of the antibody, including optimal dilutions, for other applications of interest.

We cannot guarantee that the yet-to-be-fully validated antibody will work in any application other than in an ELISA against the peptide used as immunogen and therefore cannot offer a refund if the antibody does not work in your application.
The antibody is offered at a lower price compared to a more highly validated antibody.
We are not able to provide the immunogen for the antibodies, but do provide the amino acid sequence.


These antibodies are not fully validated and we appreciate your feedback. Customer feedback is used to help generate testing methodologies which can lead to further product validation or withdrawal.
Bnc 1 is a 994 amino acid protein possessing three separated pairs of zinc fingers and a nuclear localization signal. It regulates the expression of proteins involved in chromatin structure, transcription/DNA-binding, ion-channels, adhesion/cell–cell junction, signal transduction, and intracellular transport. It also plays a role in the differentiation of spermatozoa and oocytes. It is expressed in epidermis, hair follicles, testis, ovary and foreskin, and to a lower extent in thymus, spleen, mammary glands, placenta, brain and heart.

Antigen
Amino acids 623-636 QTPEQATHNSERET of human Bnc 1 protein were used as the immunogen.

Application Notes
The amino acid sequence used as immunogen is 100% homologous in human, chimpanzee and monkey, 92% homologous in cow, 83% homologous in dog and 76% homologous in horse.

Genebank Info (Protein): NP_001708
Gene ID: 646
SwissProt: Q01954
 
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Reference
1. Vanhoutteghem, A. et al. Proc. Natl. Acad. Sci103:12423-12428 (2006).


Research purposes only. Not for diagnostic or in vivo use. This product is guaranteed to perform as indicated on the datasheet for one year from the date of purchase.


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