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Datasheet
Polyclonal Antibody to NALP9
Cat.No IMX-6343
Description NALP9
Format Sera
Unit 0.1 mL
Price(USD) 165.00
MSDS
Catalog No
:
IMX-6343
Contents
:
100 ul of crude rabbit sera with 50% glycerol and 0.025% sodium azide. Sodium azide is highly toxic.
Isotype
:
Rabbit Ig
Species
:
Human
Predicted React
:
Monkey, Mouse, Rat
Host
:
Rabbit
Application
Peptide ELISA*: 1:100-1:1000 Storage Store at -20°C.
Background NALP9 is a 991 amino acid containing cytoplasmic protein belonging to the NLRP family with a DAPIN domain, three LRR (leucine-rich) repeats and a NACHT domain. Also called NOD6, NALP9 is a novel intracellular protein involved in inflammation and apoptosis. NALP9 may play a regulatory role in the innate immune system as similar family members belong to the signal-induced multiprotein complex, the inflammasome, which activates the pro-inflammatory caspases, Caspase-1 and Caspase-5.
Antigen
Amino acids 859-875 KTLKLGHNEIGDTGVRQ of human NALP9 protein were used as the immunogen.
Application Notes
The amino acid sequence used as immunogen is 100% homologous in human (isoform CRA_b), 94% homologous in monkey, 82% homologous in mouse and 70% homologous in rat.
Reference 1. Tschopp, J. et al. Nature Rev. Molec. Cell Biol. 4:95-104 (2003). 2. Inohara, N. et al. Nature Rev. 3:371-382 (2003).
Research purposes only.
Not for diagnostic or in vivo use. This product is guaranteed to perform as indicated on the datasheet for one year from the date of purchase.
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