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E-mail: info@imgenex.com
web site: http://www.imgenex.com
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11175
Flintkote Ave., Suite E, San Diego, CA 92121 Tel: (858) 642-0978 Fax (858) 642-0937 Toll free: 1-888-723-GENE E-mail: info@imgenex.com web site: http://www.imgenex.com |
| Triptorelin Acetate | ||||||||||
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Description | |||||||||
| Triptorelin C64H82N18O13, Pyr-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2is a synthetic analogue of gonadorelin (GnRH). As a result of the substitution of the 6th amino acid residue in the native molecule, the agonistic effect is more pronounced and the plasma half-life prolongedTriptorelin Acetate is purified by proprietary chromatographic techniques. | ||||||||||
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Physical Appearance | |||||||||
| Sterile Filtered White lyophilized (freeze-dried) powder. | ||||||||||
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Formulation | |||||||||
| Triptorelin (1mg/ml) was lyophilized with no additives. | ||||||||||
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Solubility | |||||||||
| It is recommended to reconstitute the lyophilized Triptorelin in sterile 18MÙ/cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions. | ||||||||||
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Stablity | |||||||||
| Lyophilized Triptorelinalthough stable at room temperature for 3 weeks, should be stored desiccatedbelow -18 C. Upon reconstitution Triptorelinshould be stored at 4 C between 2-7 days and for future usebelow -18 C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze-thaw cycles. | ||||||||||
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Purity | |||||||||
| Greater than 98.0% as determined by: (a) Analysis by RP-HPLC. (b) Anion-exchange FPLC. (c) Analysis by reducing and non-reducing SDS-PAGE Silver Stained gel. | ||||||||||
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Dimers and Aggregates | |||||||||
| Less than 1% as determined by silver-stained SDS-PAGE gel analysis. | ||||||||||
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Endotoxin | |||||||||
| Less than 0.1 ng/µg (IEU/µg) of Triptorelin Acetate. | ||||||||||
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Protein Content | |||||||||
| Protein quantitation was carried out by two independent methods: 1. UV spectroscopy at 280 nm .2. Analysis by RP-HPLC, using a standard solution of Triptorelin as a Reference Standard. | ||||||||||
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Usage | |||||||||
| This material is offered by Imgenex for research, laboratory or further evaluation purposes. | ||||||||||
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Protein links | |||||||||
| [Pharmacokinetics and pharmacodynamics of triptorelin] [Pharmacodynamics of triptorelin] | ||||||||||
| Toll free: 1-888-723-4363 | Fax: 1.858.642.0937 | www.imgenex.com | info@imgenex.com |
| Research purposes only. Not for diagnostic or in vivo use. | |||