Imgenex Corp. develops and commercializes novel reagents for the scientific study of human biology and disease and for the production of new diagnostic assays and potential therapies of such diseases. These novel reagents include antibodies, gene and protein expression systems, and arrays of various cells and tissues for use in studies of functional genomics. Areas of biological interest at IMGENEX include cancer, apoptosis (programmed cell death), molecular signaling pathways, cellular aging, and metabolic and infectious diseases.

Tissue microarrays (TMA) represent a promising solution for scientists working to correlate gene and protein expression in normal and diseased tissue samples. First described in published research by J. Kononen et al. (Nature Medicine Vol 4. No. 7, 1998 pp. 844-847), use of TMA's has increased over the last few years as more researchers have recognized novel applications across a wide variety of scientific disciplines.

Arraying large numbers of tissues on a slide, one can more easily evaluate and correlate gene and protein expression across hundreds of tissue samples. This translates to significant savings in time through elimination of tissue acquisition, as well as money due to reduced reagent usage. Additionally, tissue arrays are compatible with many high throughput analysis systems allowing even faster data acquisition and analysis. Download the pdf version of our Histo-Array tissue array product information sheet.

IMGENEX Histo-Array tissue array slides are a practical, innovative, inexpensive, yet highly efficient method for protein and mRNA expression studies. Using Histo-Array tissue array slides, IHC staining of one slide can visualize expression patterns of different organs, or different cases of a specific human cancer-You choose!

Tissue array slides contain up to 60 samples and are available for many different diseased and normal tissues. Each slide includes patient data for all tissue samples. IMGENEX also carries human fetal, mouse, and rat organs as well.